Supplemental_Tables S1-S4

Supplemental tables from CiiiDER transcription factor enrichment analysis.

Table S1. Results from CiiiDER transcription factor enrichment analysis to analyze shared transcription factors (TFs) between the sexes during hibernation. The enriched TF binding site columns denote the number of over- and under-represented transcription factor binding sites revealed in the enrichment analysis, with either upregulated or downregulated differentially expressed (DE) genes used as input. Overlapped TFs represent the number of shared transcription factors between males and females at late hibernation (LH) vs. early hibernation (EH). Red lettering indicates the TFs whose binding site is significantly over-represented in DE genes relative to the background set. Black lettering indicates the TF whose binding site is significantly under-represented and contains binding sites more frequently in the background set relative to DE genes.

Table S2. Significantly enriched transcription factors (TFs) from CiiiDER enrichment analysis. The group column denotes the planned comparisons and direction of gene expression (upregulated or downregulated) used as input for the analysis. The enriched TF column denotes the over-represented enriched TF shared between the sexes at the planned comparison. Differentially expressed (DE) target columns denote the predicted DE genes that the TF contains enriched binding sites in, for male and female AGS.

Table S3. Results from CiiiDER transcription factor enrichment analysis to analyze sex-specific transcription factors (TFs) across hibernation. The enriched TFs column denotes the number of over- and under-represented transcription factor binding sites revealed in the enrichment analysis, with upregulated differentially expressed (DE) genes used as input. Red lettering indicates the TFs whose binding site is significantly over-represented in DE genes relative to the background set. Black lettering indicates the TF whose binding site is significantly under-represented and contains binding sites more frequently in the background set relative to DE genes.

Table S4. Significantly enriched transcription factors (TFs) from CiiiDER enrichment analysis. The enriched TF column denotes the over-represented enriched TF within a sex at the planned comparison (group column). Differentially expressed (DE) target columns denote the predicted DE genes that the TF contains enriched binding sites in, at each comparison.