Supplementary tables: An impact evaluation of two modes of care for sickle cell disease crises

These are peer-reviewed supplementary materials for the article 'An impact evaluation of two modes of care for sickle cell disease crises' published in the Journal of Comparative Effectiveness Research.Table A1: Parameters used in the model of two modes of sickle cell diseases crises careAim: To estimate the economic impacts of increased use of specialty care infusion centers for treating adults experiencing vaso-occlusive crises. Methods: A Markov model is developed to estimate the impact of expanding use of specialty care infusion centers to treat vaso-occlusive crises compared to emergency department care. Results: Access to infusion centers for sickle cell disease could result in savings over US$1.9 billion in formal medical costs and over US$2 billion in societal costs, based on uptake assumptions over 10 years. Conclusion: Expansion of adult sickle cell disease centers across the nation could lead to considerably better economic outcomes in the form of reduced costs and hospital length of stay in addition to improved clinical outcomes as reported in the existing literature.