Generation of de novo telomere end by CRISPR-based large-scale genome editing
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/DRP007046
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资源简介：
We developed the novel CRISPR/Cas9 system in the rodent malaria parasites Plasmodium berghei. We conducted the large-scale genome editing to delete the subtelomeric regions using a donor template DNA with telomere sequences. The combination of Illumina sequencing and Nanopore-based long read sequencing revealed the deletion of subtelomeric regions and extension of telomere seeding sequences.
创建时间：
2021-03-20
