five

Effect of Actn3 genotype on dexamethasone response in skeletal muscle

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE169571
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To examine the effect of alpha-actinin-3 deficiency on muscle atrophy response following dexamethasone treatment. Adult male C57BL6 WT and Actn3 null mice were given a single bolus of 20 mg/kg dexamethasone sodium phosphate by intraperitoneal injection. Controls were injected with saline. Quadriceps muscles were harvested and RNA extracted for RNA-seq analysis at 3 hr or 24 hr post injection.
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2021-07-07
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