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Additional supplementary data for "Uncertainty-aware and interpretable evaluation of Cas9-gRNA and Cas12a-gRNA specificity for fully matched and partially mismatched targets with Deep Kernel Learning""

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Zenodo2021-05-21 更新2026-05-25 收录
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Additional supplementary data for the paper. ClusterLogos.pdf - The logo sequences for each cluster of the gRNAs from LOC440792 gene. gRNA.xlsx -The set of gRNAs found in Chromosome 22 of HG38 human reference genome with corresponding estimations of cleavage efficiency and variance. A single Excel file with 16 sheets - one for each on-target model trained (DeepHF and DeepCpf1 datasets). In each sheet, there are the following fields: 1. gene - the identificator of the gene; 2. position - starting position of the gRNA target; 3. gRNA - the sequence of gRNA target; 4. strand - the strand of DNA; 5. mean - the mean cleavage efficiency estimated by a model; 6. variance - the variance of cleavage efficiency prediction.

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Zenodo
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2021-05-21
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