SDAP

SDAP is a Web server that integrates a database of allergenic proteins with various computational tools that can assist structural biology studies related to allergens. SDAP is an important tool in the investigation of the cross-reactivity between known allergens, in testing the FAO/WHO allergenicity rules for new proteins, and in predicting the IgE-binding potential of genetically modified food proteins. Using this Internet service through a browser, it is possible to retrieve information related to an allergen from the most common protein sequence and structure databases (SwissProt, PIR, NCBI, PDB), to find sequence and structural neighbors for an allergen, and to search for the presence of an epitope other the whole collection of allergens.

SDAP是一款集成变应原蛋白质数据库与多种计算工具的Web服务器，可辅助开展与变应原相关的结构生物学研究。SDAP是探究已知变应原间交叉反应性、验证新蛋白质是否符合FAO/WHO变应原性判定准则，以及预测转基因食品蛋白质IgE结合潜能的重要工具。通过浏览器访问该互联网服务，用户可从主流蛋白质序列与结构数据库（SwissProt、PIR、NCBI、PDB）中检索与变应原相关的信息，查找目标变应原的序列与结构同源邻体，还可在全部变应原集合中检索表位（epitope）的存在。

搜集汇总

背景与挑战

背景概述

SDAP是一个整合过敏原蛋白质数据库和计算工具的Web服务器，用于过敏原的结构生物学研究，支持交叉反应性分析、过敏原性规则测试和IgE结合潜力预测。