Risk assessment of drugs associated with DRESS syndrome based on publication frequency: A systematic review

We performed a systematic review to identify and risk-stratify DRESS syndrome causal drugs. 610 studies (published from 1991-2022), including 2122 validated DRESS cases, attributed to 193 drugs, were included in the analysis. Drugs were labeled as "high," "intermediate," or "low" risk based on publication frequency. This dataset includes the review's detailed search strategy and complete list of inclusion and exclusion criteria, as well as the major causal drug classes represented by included cases, and citations for all included studies.

本研究开展了一项系统评价，以识别DRESS综合征（Drug Reaction with Eosinophilia and Systemic Symptoms）的致病药物并完成风险分层。本次分析共纳入1991年至2022年发表的610项研究，涵盖2122例经验证的DRESS综合征病例，涉及193种致病药物。研究人员基于文献发表频率，将相关药物划分为高、中、低三个风险等级。本数据集包含本次系统评价的详细检索策略、完整的纳入与排除标准清单、纳入病例所代表的主要致病药物类别，以及所有纳入研究的参考文献引文。