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Functional multi-omics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE181277
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The goals of this study are to use multi-omics to design strategies to enhance efficacy of CD38-targeting immunotherapies in myeloma. We compared RNA-seq to cell surface proteomics after genetic and chemical manipulation of CD38 levels in myeloma cell lines. Examination of cell surface proteins, phosphoproteins, and RNA levels in myeloma cell lines with different levels of CD38 expression
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2025-06-04
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