Data from: Mapping of within-species segregation distortion in D. persimilis and hybrid sterility between D. persimilis and D. pseudoobscura

In contrast to the prevailing dogma in the 1990s, recent studies have suggested that an evolutionary history of segregation distortion within species may contribute to sterility in species hybrids. However, this recent work identified segregation distortion exclusively in species hybrids which may never have had an evolutionary history of segregation distortion in either parent species. We expand on previous work by using a strain of Drosophila persimilis exhibiting segregation distortion within species to generate QTL maps for segregation distortion and hybrid sterility in crosses between D. persimilis and D. pseudoobscura. The maps localize regions along the XR contributing to both phenotypes, and they indicate one region of overlap between the two maps. This overlap could provide preliminary evidence for an association between segregation distortion within species and hybrid sterility, but the localizations are currently too broad to have confidence in this conclusion. This work is a first step towards possibly supporting a genetic conflict model of speciation in this system.

与20世纪90年代的主流学术教条相悖，近期研究表明，物种内分离扭曲（segregation distortion）的演化历史可能会导致物种杂交不育。然而，该项近期研究仅在物种杂交个体中检测到分离扭曲，而这些杂交个体的两个亲本物种可能均从未存在过分离扭曲的演化历史。本研究在既往研究的基础上进行拓展，使用一株表现出物种内分离扭曲的拟暗果蝇（Drosophila persimilis）品系，针对拟暗果蝇（Drosophila persimilis）与伪暗果蝇（Drosophila pseudoobscura）的杂交组合，构建了分离扭曲与杂交不育的QTL（数量性状位点，Quantitative Trait Locus）图谱。该图谱定位了XR染色体臂上同时影响这两种表型的区域，且两张图谱存在一处重叠区域。该重叠区域可为物种内分离扭曲与杂交不育之间的关联提供初步佐证，但当前的定位区间仍过于宽泛，尚无法对该结论形成可靠支撑。本研究为在该实验体系中验证物种形成的遗传冲突模型迈出了初步探索的第一步。