Supplementary Materials

Supplementary Fig. 1: Scatter plot for ANG on Thyrotoxicosis; Supplementary Fig. 2: Forest plot for ANG on Thyrotoxicosis; Supplementary Fig. 3: Leave-One-Out Sensitivity Analysis for ANG on Thyrotoxicosis; Supplementary Fig. 4: Funnel plot for ANG on Thyrotoxicosis; Supplementary Fig. 5: The network of protein-protein interactions (PPIs) between implicated protein targets and identified causative proteins; Supplementary Fig. 6: Results of Interaction Types in Drug-Gene Interaction Analysis; Supplementary Fig. S7: Results of Directionality in Drug-Gene Interaction Analysis; Supplementary Table. 1. Sources of Data for Mendelian Randomization Analysis in the Study; Supplementary Table. 2: Details for the SNPs related to plasma proteins; Supplementary Table. 3: Genetic instruments of Thyrotoxicosis for MR; Supplementary Table. 4: MR results for plasma proteins significantly associated with Thyrotoxicosis; Supplementary Table. 5: Results of Sensitivity Analysis for Thyrotoxicosis Pathogenic Proteins; Supplementary Table. 6: Results of Drug-Gene Interaction Analysis.