Supporting Information file containing Figures A-F.

Fig. A. Average cortical thickness (mm) on the whole brain cortices of both MDD patient group and healthy control group. MDD: major depressive disorder; HC: healthy control. Fig. B. Average local surface area (mm2) on the whole brain cortices of both MDD patient group and healthy control group. MDD: major depressive disorder; HC: healthy control. Fig. C. Average local gyrification index on the whole brain cortices of both MDD patient group and healthy control group. MDD: major depressive disorder; HC: healthy control. Fig. D. The clusters with significantly different cortical thickness projected onto the average cortical surface. Lateral view and medial view by original surfaces, color-coded by t-scores. Red means that MDD has higher thickness than that of controls, and blue means that MDD has lower thickness than that of controls. P < 0.05, FDR corrected, cluster size > 200 vertices. Fig. E. The clusters with significant different local surface area projected onto the average cortical surface. Lateral view and medial view by original surfaces, color-coded by t-scores. Red means that MDD has higher surface area than that of controls, and blue means that MDD has lower surface area than that of controls. P < 0.05 FDR corrected, cluster size > 200 vertices. Fig. F. The clusters with significant different LGI projected onto the average cortical surface. Lateral view and medial view by original surfaces, color-coded by t-scores. Red means that MDD has higher local gyrification than that of controls. P < 0.05 FDR corrected, cluster size > 200 vertices.
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