Rhodium-Catalyzed C6-Selective C–H Borylation of 2‑Pyridones
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https://figshare.com/articles/dataset/Rhodium-Catalyzed_C6-Selective_C_H_Borylation_of_2_Pyridones/3487586
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资源简介：
A pyridine-directed,
rhodium-catalyzed C6-selective C–H
borylation of 2-pyridones with bis(pinacolato)diboron (pinB–Bpin)
has been developed. The reaction proceeds smoothly under relatively
mild conditions, and the corresponding C6-borylated 2-pyridones are
obtained with perfect site selectivity. Subsequent palladium-catalyzed
Suzuki–Miyaura cross-coupling is followed by the removal of
the pyridine directing group to form the C6-arylated NH-pyridone in
an acceptable overall yield.
创建时间：
2016-08-01
