Crystal structure of LSD1-CoREST in complex with PRSFLVRKR peptide

Crystal structure of LSD1-CoREST in complex with PRSFLVRKR peptide Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... Authors: Kikuchi, M, Kitagawa, H, Sato, S, Umezawa, N, Higuchi, T, Umehara, T. Deposit date: 2020-06-19 Release date: 2021-06-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Structure-Based Identification of Potent Lysine-Specific Demethylase 1 Inhibitor Peptides and Temporary Cyclization to Enhance Proteolytic Stability and Cell Growth-Inhibitory Activity. J.Med.Chem., 64, 2021与PRSFLVRKR肽结合的LSD1-CoREST复合物晶体结构。标注信息：黄素腺嘌呤二核苷酸（FLAVIN-ADENINE DINUCLEOTIDE）、甘油、赖氨酸特异性组蛋白去甲基化酶1A等。作者：Kikuchi M、Kitagawa H、Sato S、Umezawa N、Higuchi T、Umehara T。沉积日期：2020-06-19；发布日期：2021-06-23；最后修改日期：2023-11-29。实验方法：X射线衍射（2.68 Å）。引用文献：《基于结构识别强效赖氨酸特异性去甲基化酶1抑制肽并通过临时环化增强蛋白水解稳定性及细胞生长抑制活性》，J.Med.Chem., 64, 2021