five

whole-exome sequencing of NAFLD-HCC samples. Homo sapiens

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https://www.ncbi.nlm.nih.gov/bioproject/PRJDB4561
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资源简介:
The number of patients with nonalcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC) is increasing. To understand the molecular features of the tumor phenotype, we aimed to clarify the overall landscape of genetic aberrations accumulated in NAFLD-related HCC.Of 247 HCC patients who underwent hepatectomy during 2010 to 2014 at Kyoto University Hospital, 10 were diagnosed with NAFLD-HCC based on strict clinical and pathologic criteria. We analyzed the genetic aberrations of 11 NAFLD-HCC tumor samples from these 10 patients by whole-exome sequencing.
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2016-03-04
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