MMR structure at different pH
收藏ESRF Portal2028-01-01 更新2026-04-23 收录
下载链接：
https://doi.esrf.fr/10.15151/ESRF-ES-2170047627
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资源简介：
The macrophage mannose receptor (MMR) is a C-type lectin receptor expressed on immune cells, and endothelial cells. This 159 kDa glycoprotein is involved in carbohydrate recognition of pathogens, thanks to two different types of domains. MMR is an endocytic receptor and its activity and conformation are regulated by the pH, but this mechanism is still not well understood. Obtaining its structure at different pH is essential to better understand how it works and to put the basis of the development of therapies or vaccination strategies involving MMR.
提供机构：
Institut de Biologie Structurale - IBS, 71 avenue des Martyrs CS 10090, 38044, Grenoble, FRANCE; Institut de Biologie Structurale - IBS, Groupe Microscopie Electronique et Méthodes, 71 avenue des Martyrs, 38042 Grenoble, France; Institut de Biologie Structurale - IBS, Laboratoire des Proteines Membranaires, 71 avenue des Martyrs, Cs 10090, 38044 Grenoble 9, France
创建时间：
2028-01-01
