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RNA expression analysis of neuroblastoma cell lines treated with epigenetic drugs. Homo sapiens

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA317239
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资源简介:
The impact of drugs inhibiting DNA methylation (5-aza-2'-deoxycytodine, DAC) and EZH2 (EPZ-6438) on the neuroblastoma transcriptome was analyzed in two neuroblastoma cell lines. Parallel analyses investigated associated changes in histone modification and DNA methylation. Overall design: The neuroblastoma cell lines Be(2)-C and IMR5-75 were treated with DAC and EPZ-6438 in combination or alone. Controls were treated with solvent (DMSO). RNA was isolated and sequenced.
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2016-04-02
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