Additional file 6: of Formation of chimeric genes with essential functions at the origin of eukaryotes

Annotation of the 573 S-gene families detected in our study. Columns B, C, and D correspond to the EggNog automatic annotation. Column K corresponds to the manual annotation. Columns H, I, and J correspond to additional annotations for S-gene families present in the well-annotated model organism Saccharomyces cerevisiae (gene symbol, gene essentiality, and protein complexes). Columns L and M show the most abundant common protein architecture according CDD and Pfam (numbers between brackets correspond to the percentage of proteins in the given family having the given protein architecture). Column N corresponds to the cluster assignment found in Fig. 4, while columns O, P, Q, and R correspond to the ratios used to determine these clusters. Column S corresponds to the consistency between BLASTP and phylogeny strategies for taxonomic assignment. Column T corresponds to the domains removed for the ‘conservative’ component origin assignment and columns U, V, W, X, and Y correspond to the cluster and the ratios computed for the conservative assignment. The column Z indicates families for which the detection of components is restricted (restricted) to a portion of the S-gene (i.e., BAC-X/ARC-X/PROK-X). Column Z also indicates the families carrying BAC/ARC/PROK components detected by HMM (HMM-detected-component). Columns AA, AB, AC, AD, and AE correspond to the subcellular localization performed using TargetP. Columns AA, AB, AC, and AD correspond to the ratio of protein members having a mitochondrion transit peptide, chloroplast transit peptide, a signal peptide, and any other location, respectively. Column AE is the general annotation regarding whether the family is targeted or not (if more than 50% of the members of a family were predicted to contain a signal or a transit peptide, the family was considered as targeted). Columns AF and AG correspond to information about intron conservation within and between components, respectively. (XLSX 208 kb)