Engineered yeast strains expressing human glycolytic enzymes

Ewout Knibbe et al.,(Pascale Daran-Lapujade Lab, TU Delft) report on engineered yeast strains to express the human glycolysis pathway instead of the native pathway enzymes. The goal of the project is to investigate the conservation of these functions between species. The engineered yeast strains were compared to their native strains in regard to growth rate and glycolytic flux, and by means of omics such as by large-scale quantitative proteomics.