Expressed combinations of IGHV, IGHD and IGHJ segments in bovine fetal bone marrow, ileum and spleen.

A total of 645 cDNA sequences were analyzed from bone marrow, ileum and spleen. Each cell shows the numbers of cDNAs containing the JH1, JH2 and JH6 gene segment. The IGHV segment is specified by the row and the IGHD gene by the column. As an example, the top left cell shows that there were 31 cDNAs containing the combination IGHV1S3-IGHDS5-JH1 and 2 cDNAs corresponding to IGHV1S3-IGHDS5-JH6. The most commonly expressed genes were IGHV1S3, IGHDS5 and JH1. The most common combination was IGHV1S39-IGHDS5-JH1. (*) In 31 cDNAs, the ends of IGHDS2 were extensively trimmed (Table 6).