High-throughput sequencing of Precise CRISPR/Cas9-targeted Recessive Dystrophic Epidermolysis Bullosa immortalised keratinocytes (Ion Torrent)
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资源简介：
In this study, the COL7A1 on-target (exon 73) was analysed for precise CRISPR/Cas9 activity.
NGS data was assessed in CRISPR/Cas9-treated immortalised patient keratinocytes
Despite high on-target activity, high homgeneity of DSB repair outcomes was observed at the nuclease target site. This should result in efficient reframing of the gene, with minimal divergence from the wild-type sequence.
创建时间：
2019-09-20
