Autophosphorylation at serine 166 regulates RIPK1-mediated cell death and inflammation
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE131855
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资源简介：
NEMO-IEC KO mice spontaneously develop chronic colitis characterized by inflammatory gene expression. We characterized the role of RIPK1 auto-phosphorylation in the upregulation of inlflammatory genes in these mice. We used microarray to study the effect of a RIPK1S166A mutation on the gene expression profile in NEMO IEC-KO mice and detect effects on specific inflammatory genes. Colon samples were collected from 11week old mice for RNA extraction and subsequent microarray analysis.
创建时间：
2020-04-14
