Cap analysis gene analysis (CAGE) of primary AML samples harbouring FLT3-ITD mutation (human)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE149962
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The purpose of the experiment is to investigate transcriptome signatures of FLT3-ITD and TKD double mutations in AML and the underlying molecular mechanism of mutation-driven acquired resistance. We identify that 310 upregulated and 22 downregulated promoters in FLT3-ITD/D835 mutant AML cells compared to cells with FLT3-ITD (FDR<0.05). Examination of differentially expressed promoters beween FLT3-ITD AML cells and FLT3-ITD/D835 AML cells
创建时间：
2023-05-10
