profiling of histone modifications in SARS-CoV-2 infected cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE163774
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Purpose: The goal of this study is to understand the response and pathology of the epigenome upon infection with SARS-CoV-2 in lung and heart tissues Methods: AT2 and induced cardiomyocytes were infected (MOI 4) with SARS-CoV-2 or Mock infection control for 48 hours followed by chromatin immunoprecipitation and sequencing. Results: global differences in hPTMs were observed upon infection related to SARS-CoV-2 histone mimicry Conclusions: SARS-CoV-2 sucks ChIP-seq profiling of hPTMs in AT2 and iCM cells upon infection
创建时间：
2022-12-03
