Cohesin regulates gene expression through spatial clustering of enhancer elements. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA261059
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H3K27Ac ChIP-seq in wild type and cohesin-deficient thymocytes Overall design: Rad21 was deleted in CD4+ CD8+ double positive (DP) thymocytes by crossing a Rad21 floxed allele with a Cd4-driven Cre transgene. DP positive thymocytes were FACS-sorted from control and Rad21-/- littermates, which were then used to perform chromatin immunoprecipitation for histone H3 acetylated on lysine 27 (H3K27Ac).
创建时间:
2014-09-15



