AD/FTD Mutation database

AD/FTD Mutation database is a knowledge base of genetic variations in genes associated with monogenic forms of Alzheimer's disease (AD) and frontotemporal dementia (FTD). It provides curated, referenced information of 764 genetic variants in APP, PSEN1, and PSEN2 associated with AD and GRN, C9orf72, TBK1, MAPT, VCP, CHMP2B, TARDBP, and FUS associated with FTD and related diseases.

AD/FTD突变数据库（AD/FTD Mutation database）是收录与单基因亚型阿尔茨海默病（Alzheimer's disease, AD）和额颞叶痴呆（frontotemporal dementia, FTD）相关基因遗传变异的专业知识库。该库提供了经人工整理并附参考文献的764个遗传变异的相关信息，这些变异分别位于与AD相关的APP、PSEN1、PSEN2基因，以及与FTD及相关疾病相关的GRN、C9orf72、TBK1、MAPT、VCP、CHMP2B、TARDBP、FUS基因中。