Supplemental data for Conformational dynamics in the cell membrane interactions of bispecific targeted degrader therapeutics, Inganäs et al.

Supplemental data for Conformational dynamics in the cell membrane interactions of bispecific targeted degrader therapeutics, Inganäs et al. The .xslx file contains SMILES format structures and separation into E3 ligand, linker and POI ligand substructures for all 3583 analyzed PROTACs, and their original literature references (‘Overview’ sheet); molecular properties calculated from 2D structures (‘2D details’ sheet, used in Table 1); molecular properties calculated from 3D structures (‘3D details’ sheet, Figure 1); details on the PROTAC–membrane simulations (‘Membrane simulations’ sheet, Figures 3-5) and details on the experimental measurements of PROTAC–cell membrane interactions (‘Membrane affinity’ sheet, Figures 3 and 5).