RNA-seq Dataset: dual transcriptomics of human macrophages infected by Leishmania and Crithidia parasites.

Windows-compatible hyperlinked Excel file of the 224.986 CDS and their functional annotation: This dataset includes an Excel file detailing transcript IDs, read counts, TPM (Transcripts Per Million) for each transcript, and the top protein matches across various databases. It also contains protein alignments for each transcript in multiple databases (hyperlink files). These data were obtained from a dual mapping of RNA-seq samples from in vitro infections by Leishmania and Crithidia parasites. A comprehensive analysis was performed in the manuscript "Unraveling potential determinants of intracellular adaptation by Leishmania and Crithidia through a dual
transcriptomics of parasite-infected macrophages" (under review). The sequencing data was registered at Bioproject/NCBI under accession number PRJNA1098048. The raw data (reads; fastq files) were deposited at SRA/NCBI database under accession SRR37206615-SRR37206704.

本数据集包含适配Windows系统的带超链接的Excel文件，涵盖224986个编码序列（CDS，Coding DNA Sequence）及其功能注释：该Excel文件详细记录了各转录本的转录本ID、读取计数、每百万转录本数（TPM，Transcripts Per Million），以及跨多个数据库的最优蛋白质匹配结果；同时还包含各转录本在多个数据库中的蛋白质序列比对结果文件（超链接形式）。
本数据集的数据源自对利什曼原虫（Leishmania）与短膜虫（Crithidia）两种寄生虫体外感染巨噬细胞所获RNA-seq样本的双映射分析。
相关综合分析已整理为论文《通过寄生虫感染巨噬细胞的双转录组学分析揭示利什曼原虫与短膜虫的细胞内适应潜在决定因素》（"Unraveling potential determinants of intracellular adaptation by Leishmania and Crithidia through a dual transcriptomics of parasite-infected macrophages"），目前处于审稿阶段。
该测序数据已在NCBI的Bioproject数据库注册，登录号为PRJNA1098048；原始测序数据（读取序列，FASTQ格式文件）已提交至NCBI的序列读取存档（SRA）数据库，登录号范围为SRR37206615至SRR37206704。