Nitroalkanes as Thioacyl Equivalents to Access Thioamides and Thiopeptides
收藏Figshare2023-08-03 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Nitroalkanes_as_Thioacyl_Equivalents_to_Access_Thioamides_and_Thiopeptides/22776365
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The direct coupling of readily available nitroalkane and amines with just S8 and Na2S, provides an efficient way to make thioamides and thiopeptides. Mechanistic insights indicated acyl nitrite was the key intermediates. With this in-situ generated thioacylating reagents, a wide of thioamide-containing bioactive compounds were easily prepared.
创建时间：
2023-08-03
