scRNA-seq target ID - processed data and results

Supplementary data to retrospective analysis of support for known drug targets from single-cell RNA-seq data on human tissues.Contentssuppl_table_cxg_sample_metadata.post_qc.csv - sample-level metadata for data from CellXGene collections used in study suppl_table_diseases.csv - table of diseases available in CellXGene considered in study, with disease-relevant tissue annotations and reasons to excludesuppl_table_disease_target_evidence.csv - table of target-disease pairs with indication of clinical success and omic support suppl_table_odds_ratios.all.csv - Results of association analysis between omic support (`evidence`) and clinical success (`clinical status`) across diseasessuppl_table_odds_ratios.disease.csv - Results of association analysis between omic support (`evidence`) and clinical success (`clinical status`) by diseaseDEA_results - Results of differential expression analysis for each diseaseDE_celltype_{disease_id}.hvgs.csv - results of DE analysis for cell type specificity (each cell type vs rest)DE_diseasecelltype_{disease_id}.hvgs.csv - results of DE analysis for disease cell specificity (disease vs control by cell type)cxg_aggregated_scRNA - Aggregated scRNA-seq data used for DE analysis for each disease. Gene expression counts are aggregated by sample and cell type annotation.