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To assess the molecular changes associated with thymic loss, cDNA microarray and quantitative PCR analyses were used to examine the transcriptomes of the thymi of young, middle aged and old mice. Mice of both genders were examined as well as the effects of their placement on either caloric restricted (CR) or ad libitum (AL) diets. Keywords: age-, gender-, and diet- comparison 67 mice were compared according to age, gender, and diet

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