Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with d5SICS as templating nucleotide

Protein Data Bank Japan2026-03-04 更新2026-03-21 收录

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Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with d5SICS as templating nucleotide Descriptor: 5'-D(*AP*AP*CP*LHOP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP* C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOC)-3', DNA POLYMERASE I, ... Authors: Betz, K, Malyshev, D.A, Lavergne, T, Welte, W, Diederichs, K, Romesberg, F.E, Marx, A. Deposit date: 2013-10-23 Release date: 2013-12-11 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural Insights Into DNA Replication without Hydrogen Bonds. J.Am.Chem.Soc., 135, 2013

水生嗜热菌（Thermus Aquaticus）来源的DNA聚合酶I大片段与以d5SICS为模板核苷酸形成的开放二元复合物的晶体结构。序列描述：5'-D(*AP*AP*CP*LHOP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP* C)-3'，5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOC)-3'；研究对象：DNA聚合酶I（DNA POLYMERASE I）等；作者：Betz K、Malyshev D.A.、Lavergne T、Welte W、Diederichs K、Romesberg F.E.、Marx A；提交日期：2013-10-23；发布日期：2013-12-11；最后修改日期：2026-03-04；实验方法：X射线衍射（分辨率2.55埃）；引用文献：《无氢键DNA复制的结构洞察》（Structural Insights Into DNA Replication without Hydrogen Bonds），《美国化学会志》（J. Am. Chem. Soc.），第135卷，2013年

创建时间：

2013-10-23