NanoString DNA data for CNV Analysis

Quantification of DNA obtained from prostate cancer tissues and matched blood normals using the NanoString Cancer CN Panel Assay A total of 96 genes/genomic regions from the NanoString Cancer CN Panel were profiled from 65 DNA samples using nCounter. Tumour (35 + 6 replicates) and matched blood normal (n = 12 + 12 replicates) samples were obtained from radical prostatectomy-treated, intermediate-risk (NCCN definition) prostate cancer patients. Tumour tissues are either fresh frozen (n = 30) or FFPE-preserved (n = 5) and were evaluated for Gleason Score (3+3 or 3+4 or 4+3) and cellularity (>= 70%). Prior to nCounter processing, each sample underwent DNA fragmentation by one of two methods: sonication or AluI digestion.