The effects of gul1 deletion on the transcriptome of Trichoderma reesei

The morphology of filamentous fungi has a close relationship with the production of many products (e.g. industrial enzymes). In this study, we deleted gul1, which encodes a putative RNA-binding protein, in cellulolytic fungus Trichoderma reesei. The mutant showed different morphologies both on agar plates and in liquid cultures compared with its parent. RNA-seq study showed that the expression levels of genes in many biological processes were affected by gul1 deletion. Overall design: A total of 6 samples were analyzed, which include biological triplicates. The reference strain QPP was considered as a control.