Exome Sequencing of Childhood Wilms Tumor. Homo sapiens

Wilms tumor is the most common kidney cancer of children. To define the mutation spectrum of Wilms tumor, we performed whole-exome sequencing on matched tumor-normal pairs. A further set of tumor samples underwent whole exome sequencing without accompanying normal tissue. Exome data for patients giving consent to have the information available on a public, secure, database is being submitted.