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Pharmacokinetics of non-targeted mIFNα2 and targeted mIFNα2 in mouse serum after a single 5 mg/kg intravenous dose.

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Figshare2015-12-03 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Pharmacokinetics_of_non_targeted_mIFN_945_2_and_targeted_mIFN_945_2_in_mouse_serum_after_a_single_5_mg_kg_intravenous_dose_/1310944
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Non-targeted mIFNα2 had a terminal half-life of 16.2 hours, clearance of 428 mL/kg/hr, a volume of distribution of 9,996 mL/kg and an AUC(0-∞) of 11,660 hr*ng/mL. Targeted mIFNα2 had a terminal half-life of 17.1 hours, clearance of 829 mL/kg/hr, a volume of distribution of 20,432 mL/kg and an AUC(0-∞) of 6,028 hr*ng/mL.Pharmacokinetics of non-targeted mIFNα2 and targeted mIFNα2 in mouse serum after a single 5 mg/kg intravenous dose.
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2015-12-03
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