Mtb InhA complex with Pyradizinone compound 1

Mtb InhA complex with Pyradizinone compound 1 Descriptor: 4-(4-chlorophenoxy)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxamide, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Read, J.A, Gingell, H, Madhavapeddi, P, Lange, S. Deposit date: 2014-04-29 Release date: 2015-05-20 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Pyridazinones: A Novel Scaffold with Excellent Physicochemical Properties and Safety Profile for a Clinically Validated Target of Mycobacterium Tuberculosis To be Published

结核分枝杆菌（Mycobacterium tuberculosis，简称Mtb）InhA与哒嗪酮类化合物1的复合物 特征描述项：4-(4-氯苯氧基)-6-氧代-1-苯基-1,6-二氢哒嗪-3-甲酰胺、烯酰-[酰基载体蛋白]还原酶[NADH]、烟酰胺腺嘌呤二核苷酸。作者：Read J.A.、Gingell H、Madhavapeddi P、Lange S。存档日期：2014-04-29，发布日期：2015-05-20，最后修改日期：2024-05-08。实验方法：X射线衍射（分辨率2.75埃）。引用文献：《哒嗪酮类：针对结核分枝杆菌临床验证靶点的新型骨架，兼具优异理化性质与安全性》待发表。