Regio- and Enantioselective (Het)arylation of β‑Alkenyl Pyrroline to α‑Aryl-β-alkenyl Pyrrolidines
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https://figshare.com/articles/dataset/Regio-_and_Enantioselective_Het_arylation_of_Alkenyl_Pyrroline_to_Aryl-_-alkenyl_Pyrrolidines/7656596
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资源简介：
Regio- and enantioselective direct
arylation of β-alkenyl
pyrroline is reported. A wide range of electron-rich arenes and heteroarenes
reacted under mild conditions with different β-alkenyl pyrrolines
to provide structurally diverse α-aryl-β-alkenyl pyrrolidines
with very good yields and excellent regioselectivity. Enantioselective
reaction in the presence of Lewis acids and chiral phosphoric acids
provided the desired arylated product with 73% enantiomeric excess.
创建时间：
2019-01-31
