Studies of PrPres and gray matter vacuolation in scrapie-infected anchorless PrP tg44+/− mice with C57BL/6 embryonic brain grafts.
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https://figshare.com/articles/dataset/_Studies_of_PrPres_and_gray_matter_vacuolation_in_scrapie_infected_anchorless_PrP_tg44_8722_mice_with_C57BL_6_embryonic_brain_grafts_/531601
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Anchorless PrP tg44+/− mice or PrPnull (−/−) adult mice were grafted with 12–14 d embryonic brain tissue from C57BL/6 mice expressing normal anchored PrP and green fluorescent protein (GFP) [25], as described in the Methods. One month after grafting, mice were infected with scrapie by IC inoculation. Mice were euthanized at various times from 135–511 dpi, and brain tissue sections were examined by H&E staining and immunohistochemical staining for GFP and PrPres.
创建时间：
2013-02-21
