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CRISPR-screen using validation library in Cas9-het mice
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创建时间：
2025-11-13
相关数据集
filename is formated as : __.h5ad
h5ad with event frequency stored in adata.X event description saved in adata.var meta data for each Guide-Target pair saved in adata.obs
Figshare2023-06-09 更新70
Genome-scale CRISPRi Perturb-seq on both unstimulated and stimulated Jurkat cells reveals regulators of human T-cell signaling
The goal of the experiment is to identify genes involved in T-cell receptor (TCR) signaling and T-cell activation in human T cells. The Jurkat E6 cell line, engineered to express dCas9-KRAB and transd
NIAID Data Ecosystem20
Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies. Mair et al.
Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms,
NIAID Data Ecosystem20
Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]
Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe
NIAID Data Ecosystem30
THP_PVL. THP_PVL
We would like to perform a genome-scale CRISPR knockout library screen to identify loss-of-function mutations conferring PVL resistance in a human macrophage model. The human genome-wide lentiviral gR
NIAID Data Ecosystem20
