Targeting Ewing sarcoma cells via small molecule YK-4-279 treatment and downregulation of DHX9 helicase [1]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214257
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To investigate the function of DHX9 in Ewing sarcoma cell growth and proliferation, we targeted DHX9 gene by shRNA or EWS_FLI1/DHX9 interaction by YK-4-279 treatment. We performed gene expression profiling analysis using data obtained from RNA-seq of TC-71 cells treated with either DMSO or YK-4-279 2mM, or transfected with either control or DHX9 shRNAs.
创建时间:
2025-07-07



