HIF1 is a master regulator of the adaptive gene expression to hypoxia.. Homo sapiens

Total 23 samples were derived from [1] HUVEC treated in the absence (0h) or presence of hypoxia (1, 2, 4, 8, 12, and 24 hrs) to determine hypoxia-regulated gene in endothelial cells, [2] control siRNA or HIF1α siRNA transfected HUVEC cells treated in the absence or presence of hypoxia, [3] control siRNA or KDM3A siRNA transfected HUVEC cells treated in the absence or presence of hypoxia, [4] ChIP-seq data for HIF1 binding sites and histone modifications under normoxia and hypoxia in endothelial cells. Overall design: This study represents 15 Samples from the gene expression part of the study described in 1,2, and 3 above. The ChIP-Seq data mentioned above is available in GSE39089.