Data for: Bioinspired Lubricity from Surface Gel Layers

Surface gel layers on commercially-available contact lenses have been shown to reduce frictional shear stresses and mitigate damage during sliding contact with fragile epithelial cell layers in vitro. Spencer and coworkers recently demonstrated that surface gel layers could arise by polymerizing hydrogels within molds composed of low surface energy materials and near oxygen-rich interfaces from peroxidation gradients. In this study, polyacrylamide hydrogel shell probes (7.5 wt.% polyacrylamide, 0.3 wt.% methylenebisacrylamide) were polymerized in three hemispherical molds listed in order of decreasing surface energy and increasing oxygen permeability: borosilicate glass, polyetheretherketone (PEEK), and polytetrafluoroethylene (PTFE). Hydrogel probes polymerized in PEEK and PTFE molds exhibited 100´ lower elastic moduli at the surface (E*PEEK = 80 ± 31 Pa and E*PTFE = 106 ± 26 Pa, respectively) than those polymerized in glass molds (E*glass = 31,560 ± 1,570 Pa), in agreement with previo..., , , Title: **Bioinspired Lubricity from Surface Gel Layers** [https://doi.org/10.1021/acs.langmuir.3c03686](https://doi.org/10.1021/acs.langmuir.3c03686) Journal: ACS Langmuir Authors: Ahmed Al Kindi, Nemea Courelli, Kevin Ogbonna, Juan Manuel Urueña, Allison L. Chau, and Angela A. Pitenis Corresponding author: Angela Pitenis, [[e-mail]](mailto:[e-mail]) \------------------------------------------------------------------------------------------- The directory includes figures in TIFF format and CSV files to reproduce figures presented in the main text and the supporting information file. File List: csv: Fig_2.csv, Fig_3a.csv, Fig_3b.csv, Fig_4.csv, Fig_5a.csv, Fig_5b.csv, Fig_5c.csv, Fig_5d.csv, Fig_5e.csv, Fig_5f.csv, Fig_6b.csv, Fig_6cde.csv, Fig_S1.csv, Fig_S39.csv, Fig_S40.csv, Fig_S41.csv, Fig_S42.csv, Fig_S43.csv, Fig_S44.csv, Fig_S45a.csv, Fig_S45b.csv, Fig_S45c.csv tiff: Fig_6a.tiff, Fig_S3a.tiff, Fig_S3b.tiff, Fig_S3c.tiff, Fig_S4a.tiff, Fig_S4b.tiff, F...已有研究表明，市售隐形眼镜表面的凝胶层可在体外与脆弱上皮细胞层滑动接触时，降低摩擦剪切应力并减轻细胞损伤。Spencer及其团队近期证实，表面凝胶层可通过在低表面能材料制成的模具中，以及过氧化物梯度引发的富氧界面附近聚合水凝胶（hydrogel）来形成。本研究中，我们按表面能递减、氧透过率递增的顺序，选用三种半球形模具聚合聚丙烯酰胺（polyacrylamide）水凝胶壳探针（配方为7.5 wt.%聚丙烯酰胺、0.3 wt.%亚甲基双丙烯酰胺），分别为硼硅酸盐玻璃、聚醚醚酮（polyetheretherketone, PEEK）与聚四氟乙烯（polytetrafluoroethylene, PTFE）。在聚醚醚酮与聚四氟乙烯模具中聚合的水凝胶探针，其表面弹性模量（E*_PEEK=80±31 Pa、E*_PTFE=106±26 Pa）较玻璃模具中聚合的探针低约100倍（玻璃模具聚合的探针表面弹性模量E*_glass=31560±1570 Pa），这与此前的研究结果一致…… 标题：**《源自表面凝胶层的仿生润滑性能》** DOI：https://doi.org/10.1021/acs.langmuir.3c03686 期刊：ACS Langmuir（朗缪尔） 作者：Ahmed Al Kindi、Nemea Courelli、Kevin Ogbonna、Juan Manuel Urueña、Allison L. Chau、Angela A. Pitenis 通讯作者：Angela Pitenis，电子邮箱：[e-mail] ------------------------------------------------------------------------------------------- 本数据集文件夹包含TIFF格式图片与CSV格式文件，可用于复现正文及补充材料中的所有图表。 文件列表： CSV文件：Fig_2.csv、Fig_3a.csv、Fig_3b.csv、Fig_4.csv、Fig_5a.csv、Fig_5b.csv、Fig_5c.csv、Fig_5d.csv、Fig_5e.csv、Fig_5f.csv、Fig_6b.csv、Fig_6cde.csv、Fig_S1.csv、Fig_S39.csv、Fig_S40.csv、Fig_S41.csv、Fig_S42.csv、Fig_S43.csv、Fig_S44.csv、Fig_S45a.csv、Fig_S45b.csv、Fig_S45c.csv TIFF图片：Fig_6a.tiff、Fig_S3a.tiff、Fig_S3b.tiff、Fig_S3c.tiff、Fig_S4a.tiff、Fig_S4b.tiff、……