Modulation of DNA methyltransferases (DNMTs) in Spodoptera frugiperda (Sf9) cells following AcMNPV infection and its effects on the virus-cell interaction

In this study, we examined the gene expression profiles of Sf9 insect
cells following infection with baculovirus, utilizing reverse
transcription quantitative PCR (RT-qPCR) to analyze how the host cellular
machinery responds at the transcriptional level to viral invasion. Our
findings highlight the intricate regulatory mechanisms in place during
virus replication. To further understand the relationship between the host
response and viral propagation, we also quantified the dynamics of
baculovirus replication within the Sf9 cells using quantitative PCR
(qPCR). This dual approach provides a comprehensive view of both the
efficiency of viral replication and the accompanying host transcriptional
changes.