Liver_clock

Figshare2022-08-18 更新2026-04-28 收录

干细胞衰老

肝脏衰老机制

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https://figshare.com/articles/dataset/Liver_clock/20510865 数据链接链接失效反馈

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This repository contains the data to reproduce the result of the manuscript Rejuvenation of naturally aged mice by mesenchymal stem cells SHED treatment with affecting ribosomal and mitochondrial proteins

创建时间：

2022-08-18

Single Cell RNA-Sequencing using smart-seq2 of young and old murine hematopoietic stem cells

干细胞衰老

单细胞转录组学

Ageing of the hematopoietic stem cell (HSC) compartment is characterized by skewing towards the myeloid lineage and reduced stem cell function, the molecular basis of which is largely unknown. Using s

NIAID Data Ecosystem150

Additional file 6 of Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro

干细胞衰老

基因表达

Additional file 6. Table S3. List of transcripts of 120210 genes and their FPKM from transcriptome sequence in UMSC-P4 and UMSC-P9. Related to Figure 7A and 7B.

DataCite Commons2024-02-06 更新80

Tetraploidization or autophagy: The ultimate fate of senescent human endometrial stem cells under ATM or p53 inhibition

干细胞衰老

细胞命运调控

Previously we demonstrated that endometrium-derived human mesenchymal stem cells (hMESCs) via activation of the ATM/p53/p21/Rb pathway enter the premature senescence in response to oxidative stress. D

NIAID Data Ecosystem30

Transcriptomic profiling of young and aged spermatogonial stem cells (RNA-Seq)

转录组学

干细胞衰老

Spermatogonial stem cells (SSC), the foundation of spermatogenesis and male fertility, possess lifelong self-renewal activity. Aging leads to the decline in stem cell function and increased risk of pa

NIAID Data Ecosystem80

RNA-seq (SPIA-seq): Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential

干细胞衰老

转录因子重编程再生

The impact of aging on intestinal stem cells (ISCs) has not been fully elucidated. In this study, we identified widespread epigenetic and transcriptional alterations in old ISCs. Using a reprogramming

NIAID Data Ecosystem60

Liver_clock

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