PU.1 ChIP-seq in p53-/- shPU.1 AML cells following acute PU.1 restoration
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https://www.ncbi.nlm.nih.gov/sra/SRP068528
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资源简介：
We have utilized advanced RNAi technology to dynamically restore endogenous PU.1 expression and perform PU.1 ChIP-seq in p53-deficient shPU.1 AML cells in vivo. This causes rapid cell cycle shutdown and myeloid differentiation. PU.1 restoration results in regression and clearance and prolongs survival. Overall design: ChIP-seq was performed on AML-246 cells isolated from untreated or 2d Dox-treated mice
创建时间：
2019-10-31
