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Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K16acK20ac)

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Protein Data Bank Japan2024-11-27 更新2026-03-21 收录
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Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K16acK20ac) Descriptor: Bromodomain-containing protein 4, Histone H4 Authors: Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2011-11-30 Release date: 2012-01-18 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012

人类BRD4首个溴结构域(bromodomain)与双乙酰化组蛋白H4肽段(H4K16acK20ac)结合的晶体结构 描述:含溴结构域蛋白4(Bromodomain-containing protein 4)、组蛋白H4 作者:Filippakopoulos P、Felletar I、Picaud S、Keates T、Muniz J、Gileadi O、von Delft F、Arrowsmith C.H、Edwards A.M、Weigelt J、Bountra C、Knapp S、结构基因组学联盟(SGC) 提交日期:2011-11-30 发布日期:2012-01-18 最后修改日期:2024-11-27 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.02 Å 引用文献:《组蛋白识别与人类溴结构域家族的大规模结构分析》,发表于《Cell(马萨诸塞州剑桥)》,第149卷,2012年
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2011-11-30
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