PEPlife: A Repository of the Halflife of Peptides

PEPlife: Repository of Peptide Half-life Data PEPlife: Repository of Peptide Half-life Data Welcome to the official repository for PEPlife, a manually curated database of experimentally validated peptide half-life data. This resource was developed to support researchers working in peptide therapeutics, bioinformatics, computational biology, drug discovery, and pharmacokinetics. Web Server: http://crdd.osdd.net/raghava/peplife Citation Mathur, D., Prakash, S., Anand, P., Kaur, H., Agrawal, P., Mehta, A., Kumar, R., Singh, S., & Raghava, G. P. S. (2016). PEPlife: A Repository of the Half-life of Peptides. Scientific Reports, 6, 36617. https://doi.org/10.1038/srep36617 https://github.com/Piyushh1104/PEPlife.git About the Database PEPlife is a manually curated repository containing experimentally determined half-life information for therapeutic peptides. The database compiles scattered literature related to peptide stability, modifications, and pharmacokinetics into a centralized platform. The database integrates information collected from: PubMed research articles Patents DrugBank Published experimental studies PEPlife provides detailed information about peptide sequences, structures, biological activities, modifications, assays, and half-life values. Key Features Large Curated Dataset 2229 total entries 1193 unique peptides Data curated from: 335 research articles 16 patents DrugBank peptide entries