Characterization of the effects of lysosomal acid lipase deficiency on clustering of gene differentiation in CD11c+ cells
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Single cell RNA sequencing (scRNA-seq) analysis identified two distinct clusters with differential gene expression patterns, and revealed a major metabolic shift towards glucose utilization and reactive oxygen species (ROS) over-production in lal-/- CD11c+ cells. 2 samples were analyzed, lal-/- CD11c+ cells vs. lal+/+ CD11c+
