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Expression data for hiPSC-derived RPE treated with 10mM Nicotinamide or vehicle

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76923
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Nicotinamide (NAM) inhibited the expression of Age related macular degeneration (AMD) associated proteins in hiPSC-derived retinal pigment epithelium (RPE). We did the microarray analysis to examine the global impact of NAM on hiPSC-derived RPE transcriptome in order to better understand the mechanism of action of NAM. Three hiPSC-RPE lines that had been cultured with 10mM NAM or vehicle for three weeks were used for RNA extraction and hybridization on affymetrix microarrays. We treated 2 AMD hiPSC-RPE and 1 Control hiPSC-RPE line with 10mM NAM or vehicle.
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2019-03-15
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