HLA-A2-binding capability of the predicted EGFR T790M-derived peptides.
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aHLA-A2-binding capability was estimated by the increase in mean fluorescence intensity (MFI) as determined by flow cytometry after staining of RMA-S/A2 cells with anti-HLA-A2 mAb, as follows: MFI increase (%) = (MFI with a given peptide – MFI without peptides)/(MFI without peptides) X 100. The experiments were repeated three times and a representative result is shown.bWT-5 and WT-7 peptides have wild-type sequences, corresponding to the T790M-5 and T790M-7 peptides, respectively.cNA, not available.
创建时间：
2015-12-02
